SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea12c3cd3cce22fe3c963761b1760ddb6b5124449478bfcf8ccdf8f4b447d278' 
  AND token = 'jm9+f2/yYeCv23wf+tU8n6QSseBg1h2HD9rnWRVETlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}