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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4105d6804d06d3498c848fd0267481611d8694a9ae1ae2e764c97cc1aef7d640' 
  AND token = 'aNu6qZ5sVINBLF/4JryP/79dGvAmqw9+RXW1yroAP6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}