SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75946fc61fdae39247f222fd5a085f8c52e1fe5786a499365a2fc27c58159058' 
  AND token = 'IZuBgKwPFaN8xndaYedkUEdvppG7GMm2At9B+O5BwDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}