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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8ce566fbf7e0ee7d167794e593760b6d02f3a7d4d7dbe20b1b146e988103c8d' 
  AND token = 'JZTgoRgOLabfTugl+KNd82nODMjW/uSNsP4UzPo2Eco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}