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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0250985ec0025320f14e9c1a1327f1804c00bbcfdc1348b1ee867c08b5dba43' 
  AND token = 'SLPWiR16jV/9pjNMPRt8Y5Y8dDOvpZ1tNkarl9MKFB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}