SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a274e689928328b90ae86bf549ed2386534f883142d765cd14b44b072ed53d59' 
  AND token = 'I5TPLwVHn7VAeGrMkj56m6jCERy42fIG7Paq2w1bcgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}