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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b710181f9eed3c70e13389729e7390d336b16fa07108511d3d3b74d2a66cefa2' 
  AND token = 'RvLt/t27PGX8ABDQ2fpm9hYS/z2i0Ii/5aqGvNjirao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}