SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '827a563fd24e03f5f852149fe2b65093cc6e541e4c2dd36dba51b47a7f2b44dc' 
  AND token = '2ZbkglmepLeG5JXQpgjsgjKxpFbN5QV2Vxwb2tAGRPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}