SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25df065792f5f69278148f965df1498582221469d54520946e3b52bd6c07773d' 
  AND token = 'SHSW7NpW0X8f0Rf/EZvHO1vhX1SepCuqVGLysk371A0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}