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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '469bf95545c220ca85acdeb01f86979760a761a9b0a4e5597b1da027f7834c2e' 
  AND token = 'ttfJs3QQRoxZwTbV8McnSCCN1v4e6HYbiwukkDOq6ow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}