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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54d85ff42307de07b3fd330657795e1a966eb7bc4e2841dfbb84ee2b1f3e774d' 
  AND token = '+TbcK60cnK5NRaYzgptck/TPZIn3VJUXlWbr0Q5BArE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}