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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64e648db47135324274f4d733e5ae99eb7f1faf16231b70766e20cfe6ded4f31' 
  AND token = 'BcuIu83RmXIQttS/7yronboEm0BoESIYUQIQFsZKiGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}