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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b5a81ea3a0839da2fda913934746e7533dd413484853c8ec17450c2ac163e5c' 
  AND token = 't3zUEZ2PzCq5d+FTp8MBCSJzNIqxH1GbAz+qiB/tPwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}