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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '805bc36116bd3a73c72518567d461eebb643e8b8c7ab50c1cdfc9f1c46394735' 
  AND token = '3U50SzZgxQ23OCuWp4vunDkWlHZLH7l1nRrteVHcywA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}