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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1be52b10b43f04e184eade83cf02c570c7cca4ad60723378c664fed86ec7d65a' 
  AND token = '6ufv+C4RKFZqUfZHWwBbeXsqsu30q/5sM9cOck1BwYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}