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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2411d08489a1906b27e473901b77c278ecb33037457b032faab37170443dc941' 
  AND token = 'SFMW1qIz5xgrDfGDfUZ22KnDtxGnoniod0FCZrDLo0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}