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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6e04e2aaafbe9fb66d05507bca86df9c533a1a3e4a6fc215ba73d43281a09d4' 
  AND token = 'mEUOlgn1VPWNnHEWddqne8O2qP6PUiS82het+xhVkmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}