SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b2299ea04a7ecdbda51bb9514bf4455992510a1dfe16a1d8886f894d7e69277' 
  AND token = 'x0iKuInnbF1kCz2OWgWWOdgJUmT5AdfHBq5h1C5SKEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}