SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a3ad0375e9a471eb79ea58ff9de3f29deddb83d27f650be18b7457a253a1cfc' 
  AND token = 'IqJ/SLC4kVdd06quZ/msgL4R0ha9xsp1wQanf50zP7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}