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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '341a22fadf5e818ad77bc28789b77d7fa2c4c430606d4bcc8c3964ffbd0a2ac5' 
  AND token = '80+lZbNN0ua21x2NCEMaMuATuKbNH0dOlJi15dCqi1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}