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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ad43a268ff3b5b233ea6e5cd5250adbe965dc1df59b6720d59532c48f2ef86a' 
  AND token = 'J3I6hFmVMKZw4RofPzEgn3vksutLtdky70bRFWJccrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}