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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e6421199f733d432ad32467308a9016d42f46117fd3d4e1e0cdab64245cc0d5' 
  AND token = '5dkqExtnRsdnceTwwEGnBrj+VGHa4E2JdUMOiOtG9HM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}