SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ce1ce5e5ac5fa02019f676701a1969fee95ecf37f3e507eb9798b8579e49f16' 
  AND token = '24QFCTYfivXeHt9LNKoD/OBWiYWCs3lW6HgbT34CsMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}