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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c7843c31b4b6dd6812544ac6729070578d2ff4f977339d649b7ff45ccb192a2' 
  AND token = 'IOg7X71MAGOMOoFKARvu9BNxTyxqbIYBFTvyjszc4K4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}