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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d8e9c481180505577f69963f76775e2c96155f68889cf0f4ae7acdf601a186c' 
  AND token = 'UXhZpO+ef25iCRJQmnCDrsZm2fDTfwBg88d7Gl9uikY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}