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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22015ba9260d8fd9304de00b1acd368681f056b87b2e194fd4369a32a57dc6b6' 
  AND token = '7feyT7GB1aFQApVmcAZ/Shy+/o8a/1lUm2FD1LGScpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}