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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e60b85dc9aab8b1cd4de175db3456024c1ead77686ffd582046fb82d2405dfc' 
  AND token = '4NNhKG3JEskVzbHNfl7+5P8xbE8Izm8OWeOlpinAGWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}