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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8290f4a22e5a4f737e27a6c54f8acde88a7c4f1dac1cd601bf1567c4e4a0ecf4' 
  AND token = 'b3Djf2nA0emJ0PKdbV0VivthAxqIIdQ6Q/7tcn0eEi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}