SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3780e105081388c020b80cf050034aafcb97ccc16b00149b213e35d73b8e8b63' 
  AND token = 'FubmqmU0tFxJGRvgrXvDt+cPHPgChly2mvko9pjzgNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}