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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '437199b233ec25e22d2a5e022225c4f276d6a3a72864a3d3e4b834d67354bf69' 
  AND token = 'qxwREsZK+a6qODNqWYVTvcAAPVRzt7e0tQrYGZ+gqpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}