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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '889009125bf3e3e08f809ac7040c746ab521aaf36a5e8662d719c0f25b8fca1f' 
  AND token = '6iFXikAQdh0tGKE7xucBDGWU8XCOQhu7NBCu37Y5mV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}