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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6af23ac4c1a397293b9326f1c715ff53e864f4a811c060d6bb4837566def2c81' 
  AND token = 'eYYUP7ofOSh8LhBSr1HK0ReP6NEiA2XxQowGXMVjlXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}