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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4945b33b4b9ae99c26fcc2990a2502f73a586a3a71d34cadc106f4f09d766ca4' 
  AND token = 'wU517LSN6hda3HylN4n3uxQcubDWoZ2ozodoCDcOVOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}