SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8678e680bd16a27f0baa3b116e8fd39b0c7a431cb9cbc982216c314d8bc20be' 
  AND token = '8mTAlCABWwm+YYyk5eCRW9tcMDUazuZsePxq7+8E4nM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}