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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8168553df5d3b8000f7a84b62e4caf456daa862c25a1ce4ce7da6905d31f7079' 
  AND token = 'OPmwVJ6u6/5BVtiEw/4kl9BUbpYlx2nb8INpTCUBW5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}