SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '135bc434045ee000b471468e656e18ffa879ea21e176c75d775e37d4127b09a5' 
  AND token = 'Oc+YQBr9CnWw3+o2xXnUx6y29sBhuT31AiICMI64eOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}