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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '878946ef3b80a832919e75392e6e2c5b0316a3113c9feabd0242a4881ad9c72b' 
  AND token = 'QHHLu91+lML25AEydpbVhIMTjbqGHJCcGNPtxLRLQxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}