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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5184e9b9cfd779e3b0a8db388421959a116f5b20bf218e160e69f0f49122b3b2' 
  AND token = 'PtqY+rwOxDMMmpA/diO/AHafy+ymMEVtrw8ua5vBwjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}