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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '895bc4c77745faf6ca9d5b6c80c78c31bcac9d6f40a2d7a99b14808a314d86ca' 
  AND token = 'LEbtXpz7AM7+0MAMKXLqs+p4AOnFUnT4nPopGKGL4wM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}