SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c1b0417ba1381699ddfccecd58d1c79bed6f34f7a64cd95b6b9e146c77e44a7' 
  AND token = 'zzI1HnQ6lmLWlgYXr88qygOPB00SxN+wm3P8kU1ZEbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}