SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0449c2332e6944584dedb6e21e85d084bbc32556bdae66b083bd911686ffcb76' 
  AND token = 'IpENYnBfD7zDfaPNZzx01EvlWE8bA0ndVvmG4R0fUA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}