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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3211c21f556e91cbef8283828ec026e36dae7f5d2f4b6138096ab1d322e58da0' 
  AND token = 'xGZnS4bz+8Yo3L0kr9fyQjgcmXW6ajIN3rBNxqUbXhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}