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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d60ef5ae11cf9309ac4fdabed3dc1781f9c394fb4746b10de36601ffacb8972' 
  AND token = 'nJPKuh/QWeGSHBmCAgzXxuWa6y4XB4098zMxjtPJFy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}