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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9e1ff062cabc096ba1c7ad027085ac702899bef2886df5e959ae43faa572dd9' 
  AND token = 'CIzTV+/jEQ80rmCkyWfQhSVOAKuu1XMp/zA3fbx50kY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}