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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a6524661f080240aa7ef566dd22f083821fdd3fd50fcfb275ac763da857ab66' 
  AND token = 'b3wZEuKRoxYIgR5v9V6uyn7KguJjzOxkjL0bFAcU59w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}