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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7867728ab3ea81bfc6e072c1ff9c4ad685aa7d6ad77b6ae8b8d98470b0d9f5b1' 
  AND token = 'UY3uY7mlLkPKUFS+3FP4wRAK5SSPdL1E362STKgWOrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}