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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6379a9afba8b4c82bd0fccb7f3d2cdca6ddf886973dc58f8cb8e9e923d4de8ad' 
  AND token = '+hKDh9TtStCPG1Ia5Fy40FhN7QWpftWy1gvbDX8A0kE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}