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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55e6fa04171d5d5ec317f34d4686ea5f64ee99cda17b3b44d34b13ac58174577' 
  AND token = 'Qbym/hyXzmR4qJg32a/MM1DrU8+8IYit1f0KX3ZejSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}