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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '046cb073251d308f698d0ba64c69986453dd5b57bdb1ee4cf1feb81156b553a2' 
  AND token = 'jISpmZ0WANEsiHywv2rdZtj35s17ECuEY8cpvZrHdnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}