SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '786192d7201ad866bbd2ce3c95b550d0229207e3d37d103b352c7ad7efcf2c4d' 
  AND token = '+3/eKhXeQHwWtgeAxXIUjeCgFeyLe4NEYZszdbDYWmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}